Pap T, Retih I, Kajtár P, Kelényi G
Acta Morphol Acad Sci Hung. 1980;28(4):407-16.
In the period between 1960--1978 36 children dead with acute lymphoblastic leukaemia (ALL) were studied. Nine cases were found to be in pathological remission, i.e., without any leukaemia infiltrations (7 of these were seen in the last 5 years). The remaining 27 could be divided into two groups on the basis of nuclear structure: in 20 cases the lymphoblastic nuclei were round or oval and their convolution was pycnotic, "highly convoluted", or lobulated, in 7 the nuclei were round or oval and their convolution was slight. The survival was 10.8 months in the first and 3.6 months in the second group. Although the origin and the degree of differentiation of the cells of these two groups are not clearly known, it seems that the two types represent different stages of T-lymphoblast evolution.
在1960年至1978年期间，对36例死于急性淋巴细胞白血病（ALL）的儿童进行了研究。发现9例处于病理缓解期，即无任何白血病浸润（其中7例出现在过去5年）。其余27例可根据核结构分为两组：20例淋巴细胞核呈圆形或椭圆形，其卷曲呈固缩状、“高度卷曲”或分叶状；7例细胞核呈圆形或椭圆形，其卷曲轻微。第一组的生存期为10.8个月，第二组为3.6个月。虽然这两组细胞的起源和分化程度尚不清楚，但这两种类型似乎代表了T淋巴细胞母细胞进化的不同阶段。
