Bonsignore G, Bellia V, Ferrara G, Mirabella A, Rizzo A, Sciarabba G
Eur J Respir Dis Suppl. 1980;106:29-34.
Maximum expiratory flows at 50% of vital capacity while breathing air and a He-O2 mixture and delta Vmax50 observed during three sittings (morning, noon and morning the day after) in reference subjects and in patients with bronchial hyperreactivity were submitted to statistical analysis by between sittings comparison, looking for correlation coefficients, paired "t" test and variation coefficient. Results of paired "t" test ruled out the influence of fatigue and of training in performing forced expiratory manoeuvres. Correlation coefficients relevant to absolute flows are highly significant in both groups, whereas coefficients of variation are satisfactory in reference subjects and slightly higher although still acceptable in patients with bronchial hyperreactivity. As far as delta Vmax50 is concerned, the results of statistical analysis are positively unacceptable, thus demonstrating that this arithmetic manipulation of absolute flows is the ground for a poor reproducibility of results.
在静息状态及吸入氦氧混合气时，肺活量50%时的最大呼气流量以及在三次测试（早晨、中午和次日早晨）期间在健康对照者和支气管高反应性患者中观察到的Vmax50差值，通过不同测试之间的比较进行统计分析，寻找相关系数、配对“t”检验和变异系数。配对“t”检验的结果排除了疲劳和进行用力呼气动作训练的影响。两组中与绝对流量相关的相关系数均高度显著，而变异系数在健康对照者中令人满意，在支气管高反应性患者中略高但仍可接受。就Vmax50差值而言，统计分析结果完全不可接受，从而表明对绝对流量的这种算术处理是结果再现性差的原因。
