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奥克兰地区十年多发性肌炎回顾性研究。

Retrospective study of polymyositis in Auckland over 10 years.

作者信息

Ogle S

出版信息

N Z Med J. 1980 Dec 10;92(673):433-5.

PMID:6937784
Abstract

Twenty-nine patients with polymyositis and dermatomyositis seen at the three main hospitals in Auckland between 1967 and 1977 have been reviewed. Of the five diagnostic criteria used, weakness of proximal muscles (including neck flexors) was the single most important clinical diagnostic feature. The certainty of diagnosis was increased if investigations included a range of muscle enzymes, electromyography and muscle biopsy. The incidence of underlying malignancy was 10 percent. Patients with polymyositis or dermatomyositis with an associated connective tissue disorder responded better to treatment and pursued a more benign course.

摘要

对1967年至1977年间在奥克兰三家主要医院就诊的29例多发性肌炎和皮肌炎患者进行了回顾性研究。在所使用的五项诊断标准中,近端肌肉(包括颈部屈肌)无力是最重要的单一临床诊断特征。如果检查包括一系列肌肉酶、肌电图和肌肉活检,诊断的确定性会增加。潜在恶性肿瘤的发生率为10%。伴有相关结缔组织疾病的多发性肌炎或皮肌炎患者对治疗反应更好,病程更良性。

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