高渗培养条件下大鼠红白血病细胞的红系分化与定向分化

Erythroid differentiation and commitment in rat erythroleukemia cells with hypertonic culture conditions.

作者信息

Yamaguchi Y, Kluge N, Ostertag W, Furusawa M

出版信息

Proc Natl Acad Sci U S A. 1981 Apr;78(4):2325-9. doi: 10.1073/pnas.78.4.2325.

DOI:10.1073/pnas.78.4.2325

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC319338/

Abstract

Cell cultures of 7,12-dimethylbenz[a]anthracene-induced rat erythroleukemia can be stimulated to synthesize hemoglobin when cultured in hypertonic media. During hypertonic treatment the intracellular osmotic conditions immediately readjust to those of the extracellular medium. None of the Friend virus-induced mouse erythroleukemia cell lines was inducible for differentiation with the same hypertonic culture conditions used for rat cells. Earliest commitment to erythroid terminal differentiation by hypertonic treatment of cells grown in either Eagle's or Joklik's medium occurs coincident with the commitment induced by hexamethylenebisacetamide. These results make it likely that induction of differentiation in rat erythroleukemia cells is a cell membrane-mediated event.

摘要

用7,12-二甲基苯并[a]蒽诱导的大鼠红白血病细胞培养物，在高渗培养基中培养时可被刺激合成血红蛋白。在高渗处理期间，细胞内的渗透条件会立即重新调整至与细胞外培养基相同。对于用于大鼠细胞的相同高渗培养条件，没有一种Friend病毒诱导的小鼠红白血病细胞系可被诱导分化。在伊格尔氏培养基或乔克利克氏培养基中生长的细胞经高渗处理后，最早向红系终末分化的定向与由六甲撑双乙酰胺诱导的定向同时发生。这些结果表明，大鼠红白血病细胞的分化诱导可能是一个细胞膜介导的事件。

相似文献

1

Erythroid differentiation and commitment in rat erythroleukemia cells with hypertonic culture conditions.高渗培养条件下大鼠红白血病细胞的红系分化与定向分化

Proc Natl Acad Sci U S A. 1981 Apr;78(4):2325-9. doi: 10.1073/pnas.78.4.2325.

2

Inhibition of erythroid differentiation of mouse erythroleukemia cells by a macrophage product(s).

Blood Cells. 1987;13(1-2):161-9.

3

Dimethyl sulfoxide-induced differentiation of Friend erythroleukemia cells in the absence of cytokinesis.在无胞质分裂情况下二甲基亚砜诱导的弗氏红白血病细胞分化

Cancer Res. 1979 Oct;39(10):4058-63.

4

Growth and differentiation of Friend erythroleukemia cells in serum-free culture.无血清培养条件下弗氏红白血病细胞的生长与分化

Leuk Res. 1983;7(5):591-7. doi: 10.1016/0145-2126(83)90130-3.

5

Inducers of erythroid differentiation in K562 human leukemia cells.K562人白血病细胞中红细胞分化诱导剂。

Exp Hematol. 1981 Jan;9(1):32-7.

6

Induction of erythroid differentiation of murine erythroleukemia cells by nicotinamide and related compounds.烟酰胺及相关化合物诱导小鼠红白血病细胞向红系分化

Proc Natl Acad Sci U S A. 1979 Dec;76(12):6411-4. doi: 10.1073/pnas.76.12.6411.

7

Lipid changes associated with erythroid differentiation of Friend erythroleukemia cells.

Toxicol Pathol. 1987;15(2):170-7. doi: 10.1177/019262338701500207.

8

Effect of hexamethylene bisacetamide on the commitment to differentiation of murine erythroleukemia cells.六亚甲基双乙酰胺对小鼠红白血病细胞分化定向的影响。

Cancer Res. 1977 Feb;37(2):440-4.

9

Amiloride inhibits murine erythroleukemia cell differentiation: evidence for a Ca2+ requirement for commitment.氨氯吡咪抑制小鼠红白血病细胞分化：分化起始需要钙离子的证据。

Proc Natl Acad Sci U S A. 1980 Oct;77(10):5948-52. doi: 10.1073/pnas.77.10.5948.

10

Erythroid potentiating activity of tissue inhibitor of metalloproteinases on the differentiation of erythropoietin-responsive mouse erythroleukemia cell line, ELM-I-1-3, is closely related to its cell growth potentiating activity.金属蛋白酶组织抑制剂对促红细胞生成素反应性小鼠红白血病细胞系ELM-I-1-3分化的红细胞增强活性与其细胞生长增强活性密切相关。

Exp Hematol. 1993 Jan;21(1):169-76.

引用本文的文献

1

Role of endogenous cat retrovirus in cell differentiation.内源性猫逆转录病毒在细胞分化中的作用。

Proc Natl Acad Sci U S A. 1982 Dec;79(23):7371-5. doi: 10.1073/pnas.79.23.7371.

2

The natural history of a family of transplantable melanomas in hamsters.仓鼠可移植黑色素瘤家族的自然病史。

Cancer Metastasis Rev. 1988 Jun;7(2):95-118. doi: 10.1007/BF00046481.

本文引用的文献

1

Commitment to differentiation in Friend cells and initiation of globin mRNA synthesis occurs during the G1 phase of the cell cycle.在Friend细胞中向分化的转变以及珠蛋白mRNA合成的起始发生在细胞周期的G1期。

Exp Cell Res. 1980 Feb;125(2):459-70. doi: 10.1016/0014-4827(80)90140-8.

2

Hemoglobin synthesis in murine virus-induced leukemic cells in vitro: stimulation of erythroid differentiation by dimethyl sulfoxide.体外小鼠病毒诱导白血病细胞中的血红蛋白合成：二甲基亚砜对红系分化的刺激作用

Proc Natl Acad Sci U S A. 1971 Feb;68(2):378-82. doi: 10.1073/pnas.68.2.378.

3

Induction of leukemia in rat by pulse doses of 7,12-dimethylbenz(a)anthracene.脉冲剂量的7,12-二甲基苯并(a)蒽诱发大鼠白血病

Proc Natl Acad Sci U S A. 1966 Jan;55(1):74-81. doi: 10.1073/pnas.55.1.74.

4

Synthesis of mouse haemoglobin and globin mRNA in leukaemic cell cultures.白血病细胞培养物中小鼠血红蛋白和珠蛋白mRNA的合成。

Nat New Biol. 1972 Oct 25;239(95):231-4. doi: 10.1038/newbio239231a0.

5

Studies of cellular differentiation by automated cell separation. Two model systems: Friend virus-transformed cells and Hydra attenuata.

J Histochem Cytochem. 1976 Jan;24(1):332-47. doi: 10.1177/24.1.1254928.

6

A new group of potent inducers of differentiation in murine erythroleukemia cells.一组新型的强效诱导小鼠红白血病细胞分化的物质。

Proc Natl Acad Sci U S A. 1976 Mar;73(3):862-6. doi: 10.1073/pnas.73.3.862.

7

Induction of erythroid differentiation by dimethylsulfoxide in cells infected with Friend virus: relationship to the cell cycle.二甲基亚砜对感染弗氏病毒的细胞中红细胞分化的诱导作用：与细胞周期的关系

Proc Natl Acad Sci U S A. 1975 Jan;72(1):28-32. doi: 10.1073/pnas.72.1.28.

8

Induction by ouabain of hemoglobin synthesis in cultured Friend erythroleukemic cells.哇巴因诱导培养的弗氏红白血病细胞合成血红蛋白

Cell. 1976 Nov;9(3):375-81. doi: 10.1016/0092-8674(76)90082-9.

9

Commitment to erythroid differentiation by friend erythroleukemia cells: a stochastic analysis.Friend红白血病细胞向红系分化的趋向性：一项随机分析。

Cell. 1976 Oct;9(2):221-9. doi: 10.1016/0092-8674(76)90113-6.

10

Dimethylsulfoxide-induced differentiation and hemoglobin synthesis in tissue cultures of rat erythroleukemia cells transformed by 7,12-dimethylbenz(a)anthracene.二甲基亚砜诱导经7,12-二甲基苯并(a)蒽转化的大鼠红白血病细胞组织培养物中的分化及血红蛋白合成。

Proc Natl Acad Sci U S A. 1976 Apr;73(4):1237-40. doi: 10.1073/pnas.73.4.1237.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

文档翻译

学术文献翻译模型，支持多种主流文档格式。