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一例系统性红斑狼疮合并铁粒幼细胞性贫血，最终发展为红白血病。

A case of systemic lupus erythematosus with sideroblastic anaemia terminating in erythroleukaemia.

作者信息

Ng H S, Ng H W, Sinniah R, Feng P H

出版信息

Ann Rheum Dis. 1981 Aug;40(4):422-6. doi: 10.1136/ard.40.4.422.

DOI:10.1136/ard.40.4.422
PMID:6942789
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1000742/
Abstract

A case of systemic lupus erythematosus is described in which for 10 years the only significant findings were erythema multiforme and vasculitis. Gross hepatosplenomegaly with persistent pancytopenia developed, and bone marrow examination revealed the presence of sideroblasts. The patient's condition deteriorated, and subsequently she developed a severe bleeding tendency, terminating in erythroleukaemia.

摘要

报告一例系统性红斑狼疮患者，该患者10年来唯一显著的表现为多形性红斑和血管炎。之后出现肝脏和脾脏肿大伴持续性全血细胞减少，骨髓检查发现有环形铁粒幼细胞。患者病情恶化，随后出现严重出血倾向，最终发展为红白血病。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f30/1000742/541f26e40352/annrheumd00105-0111-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f30/1000742/b721a5559cc3/annrheumd00105-0109-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f30/1000742/9540a805f77f/annrheumd00105-0110-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f30/1000742/6a5512dbd7cc/annrheumd00105-0110-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f30/1000742/adc1b051d2bc/annrheumd00105-0111-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f30/1000742/baa2a2509402/annrheumd00105-0111-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f30/1000742/541f26e40352/annrheumd00105-0111-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f30/1000742/b721a5559cc3/annrheumd00105-0109-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f30/1000742/9540a805f77f/annrheumd00105-0110-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f30/1000742/6a5512dbd7cc/annrheumd00105-0110-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f30/1000742/adc1b051d2bc/annrheumd00105-0111-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f30/1000742/baa2a2509402/annrheumd00105-0111-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f30/1000742/541f26e40352/annrheumd00105-0111-c.jpg

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A case of systemic lupus erythematosus with sideroblastic anaemia terminating in erythroleukaemia.一例系统性红斑狼疮合并铁粒幼细胞性贫血，最终发展为红白血病。
Ann Rheum Dis. 1981 Aug;40(4):422-6. doi: 10.1136/ard.40.4.422.
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Sangre (Barc). 1978;23(3):369-83.
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Erythroblast kinetics in pernicious anaemia, erythroleukaemia and sideroblastic anaemia.恶性贫血、红白血病和铁粒幼细胞贫血中的成红细胞动力学。
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[Maturation arrest of erythroid series at preleukemic stage: A report of three cases (author's transl)].白血病前期红系成熟停滞：三例报告（作者译）
Rinsho Ketsueki. 1974 Oct;15(10):1142-8.

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本文引用的文献

1
The auto-immune hemolytic anemia of malignant lymphocytic disease.恶性淋巴细胞疾病的自身免疫性溶血性贫血
Blood. 1955 Mar;10(3):197-227.
2
SIDEROBLASTIC ANAEMIA: IS THIS A MALIGNANCY?铁粒幼细胞性贫血：这是一种恶性肿瘤吗？
Br J Haematol. 1965 Jan;11:52-8. doi: 10.1111/j.1365-2141.1965.tb00084.x.
3
Leukemia and auto-immunization- some possible relationships.白血病与自身免疫——一些可能的关系。
Blood. 1959 Oct;14:1151-8.
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Dermatomyositis in cancer: a possible etiological mechanism.癌症相关性皮肌炎：一种可能的病因机制。
Cancer. 1959 Jul-Aug;12(4):648-50. doi: 10.1002/1097-0142(195907/08)12:4<648::aid-cncr2820120404>3.0.co;2-0.
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Auto-immune hemolytic anemia arrested by removal of an ovarian teratoma: review of the literature and report of a case.
Ann Intern Med. 1957 Nov;47(5):1002-7. doi: 10.7326/0003-4819-47-5-1002.
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Immunologic aberrations in the Di Guglielmo syndrome.迪古列尔莫综合征中的免疫异常。
Blood. 1966 Nov;28(5):634-49.
7
A new observation in the clinical spectrums of erythroleukemia. A report of 46 cases.红白血病临床谱的一项新观察。46例报告。
Am J Med. 1978 May;64(5):765-72. doi: 10.1016/0002-9343(78)90515-6.