Petrakis N L, Ernster V L, Sacks S T, King E B, Schweitzer R J, Hunt T K, King M C
J Natl Cancer Inst. 1981 Aug;67(2):277-84.
The epidemiology of breast fluid secretion was studied on the basis of nipple aspirates of breast fluid obtained from 3,929 nonlactating women of various racial groups. The results confirmed and extended earlier findings by our group: Variation in the proportion of secretors was related to most breast cancer risk factors, including age, race, age at menarche, age at first pregnancy, age at menopause, clinically diagnosed fibrocystic disease, menopausal estrogen use, and cerumen phenotype. Secretory activity as measured by nipple aspiration appeared to reflect hormonal and genetic effects on breast epithelium.
基于从3929名不同种族的非哺乳期女性获取的乳头吸出液，对乳腺分泌液的流行病学进行了研究。结果证实并扩展了我们团队早期的发现：分泌者比例的变化与大多数乳腺癌风险因素相关，包括年龄、种族、初潮年龄、首次怀孕年龄、绝经年龄、临床诊断的纤维囊性疾病、绝经后雌激素使用情况以及耳垢表型。通过乳头抽吸测量的分泌活性似乎反映了激素和基因对乳腺上皮的影响。
