Wenzl S, Sumper M
Proc Natl Acad Sci U S A. 1981 Jun;78(6):3716-20. doi: 10.1073/pnas.78.6.3716.
A sulfated cell surface glycoprotein with an apparent molecular weight of 185,000 is synthesized in the multicellular organism Volvox only during the limited period of embryogenesis. The lifetime of sulfate residues on this glycoprotein is very short (half-life about 20 min). Production of this sulfated glycoprotein sharply decreases to a minimum shortly before the onset of the differentiating cell cleavage--e.g., in asexual development, before the 32-cell embryo divides. It is demonstrated that the sulfated glycoprotein behaves in many respects as would the hypothetical cell surface component postulated by a recently published model [Sumper, M. (1979) FEBS Lett. 107, 241-246], which proposes an explanation for the cell-counting mechanism and the spatial control of differentiation that is operative in Volvox embryogenesis.
一种表观分子量为185,000的硫酸化细胞表面糖蛋白仅在多细胞生物团藻胚胎发生的有限时期内合成。这种糖蛋白上硫酸根残基的寿命非常短（半衰期约20分钟）。在分化细胞分裂开始前不久，这种硫酸化糖蛋白的产生急剧减少至最低水平——例如，在无性发育中，在32细胞胚胎分裂之前。结果表明，这种硫酸化糖蛋白在许多方面的行为与最近发表的一个模型[Sumper, M. (1979) FEBS Lett. 107, 241 - 246]所假设的细胞表面成分相似，该模型对团藻胚胎发生中起作用的细胞计数机制和分化的空间控制提出了解释。
