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Antitumor activity of picolinic acid in CBA/J mice.

作者信息

Leuthauser S W, Oberley L W, Oberley T D

出版信息

J Natl Cancer Inst. 1982 Jan;68(1):123-6.

PMID:6948122
Abstract

The growth of a solid tumor induced by im implantation of Ehrlich ascites tumor cells in inbred CBA/J mice was retarded by treatment with an iron chelator, picolinic acid (PLA). Survival of the mice was also significantly increased after PLA treatment. However, the iron chelator deferoxamine had no such effects; tumor growth was slightly enhanced, and survival was decreased.

摘要

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