Winston M
ASDC J Dent Child. 1982 Jan-Feb;49(1):56-9.
Atherosclerosis is a multifactorial disease. There are many theories surrounding its pathogenesis, none of which is more popular than the "lipid" hypothesis. There is an extensive body of evidence from experimental, epidemiological and pathological studies linking diet to plasma cholesterol on the one hand and plasma cholesterol to heart disease on the other. These data suggest strongly that education of the public about diet modification as one means of reducing CHD risk is a safe, appropriate and feasible approach to the prevention of the disease at the present time. The recommendations to the public are to reduce the fat content of their diets, specifically saturated fats, and limit the daily intake of dietary cholesterol to 300 mgs/day.
动脉粥样硬化是一种多因素疾病。围绕其发病机制有许多理论,其中没有一个比“脂质”假说更流行。一方面,从实验、流行病学和病理学研究中有大量证据将饮食与血浆胆固醇联系起来,另一方面又将血浆胆固醇与心脏病联系起来。这些数据有力地表明,目前向公众宣传通过改变饮食来降低冠心病风险是预防该疾病的一种安全、合适且可行的方法。向公众的建议是减少饮食中的脂肪含量,特别是饱和脂肪,并将每日膳食胆固醇摄入量限制在300毫克/天。