Mishina T, Watanabe H, Miyakoda K, Araki H, Fujiwara T, Kobayashi T
Tohoku J Exp Med. 1978 Jul;125(3):303-4. doi: 10.1620/tjem.125.303.
We examined the amount of 5-Fu absorbed through the gastric epithelium after oral administration in both dogs and patients with bladder tumors. The concentrations of 5-Fu in the serum, bladder wall, tumor mass and regional lymphnodes were sufficiently high to suppress the growth of tumor cells.
我们检测了犬类和膀胱肿瘤患者口服给药后通过胃上皮吸收的5-氟尿嘧啶(5-Fu)量。血清、膀胱壁、肿瘤块和区域淋巴结中的5-Fu浓度足以抑制肿瘤细胞的生长。