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1
Serum profiles of methotrexate after its administration in children with acute lymphoblastic leukaemia.甲氨蝶呤在急性淋巴细胞白血病患儿中给药后的血清谱。
Br J Cancer. 1982 Feb;45(2):300-3. doi: 10.1038/bjc.1982.47.
2
Unpredictable serum levels after oral methotrexate in children with acute lymphoblastic leukaemia.急性淋巴细胞白血病患儿口服甲氨蝶呤后血清水平不可预测。
Cancer Chemother Pharmacol. 1979;3(2):117-20. doi: 10.1007/BF00254982.
3
Pharmacokinetics of oral and intramuscular methotrexate in children with acute lymphoblastic leukaemia.急性淋巴细胞白血病患儿口服及肌内注射甲氨蝶呤的药代动力学
Cancer Chemother Pharmacol. 1987;20(3):243-7. doi: 10.1007/BF00570494.
4
Letter: Altered plasma pharmacokinetics of methotrexate administered intrathecally.信函：鞘内注射甲氨蝶呤后血浆药代动力学改变
Lancet. 1975 Feb 22;1(7904):465-6. doi: 10.1016/s0140-6736(75)91546-9.
5
Oral methotrexate is as effective as intramuscular in maintenance therapy of acute lymphoblastic leukaemia.口服甲氨蝶呤在急性淋巴细胞白血病维持治疗中与肌肉注射一样有效。
Arch Dis Child. 1987 Feb;62(2):172-6. doi: 10.1136/adc.62.2.172.
6
Can food influence the absorption of methotrexate in children with acute lymphoblastic leukaemia?
Lancet. 1980 Nov 1;2(8201):944-6. doi: 10.1016/s0140-6736(80)92105-4.
7
Methotrexate and folate content of erythrocytes in patients receiving oral vs intramuscular therapy with methotrexate.接受甲氨蝶呤口服与肌内注射治疗的患者红细胞中甲氨蝶呤和叶酸的含量
J Pediatr. 1984 Jan;104(1):131-3. doi: 10.1016/s0022-3476(84)80610-1.
8
High-dose methotrexate in acute lymphocytic leukemia.大剂量甲氨蝶呤用于急性淋巴细胞白血病治疗
Cancer Treat Rep. 1977 Jul;61(4):727-31.
9
[Therapeutic management of remissions in acute lymphoblastic leukemia in children].[儿童急性淋巴细胞白血病缓解期的治疗管理]
Pol Tyg Lek. 1970 Nov 2;25(44):1670-2.
10
Bone-marrow toxicity of methotrexate: a reassessment.甲氨蝶呤的骨髓毒性：重新评估
Br J Haematol. 1973 May;24(5):625-31. doi: 10.1111/j.1365-2141.1973.tb01688.x.

引用本文的文献

1
Serum profiles and safety of intermediate-dose (500-1,000 mg) methotrexate following IV and IM administration.
Cancer Chemother Pharmacol. 1983;11(3):188-90. doi: 10.1007/BF00254202.
2
Modification of oral methotrexate absorption in children with leukemia.
Cancer Chemother Pharmacol. 1984;12(2):131-3. doi: 10.1007/BF00254605.

本文引用的文献

1
Increased level of dihydrofolic reductase in leucocytes of patients treated with amethopterin.接受氨甲蝶呤治疗的患者白细胞中二氢叶酸还原酶水平升高。
Nature. 1962 Jan 13;193:140-2. doi: 10.1038/193140a0.
2
Absorption of methotrexate under standardized conditions in children with acute lymphoblastic leukaemia.急性淋巴细胞白血病患儿在标准化条件下甲氨蝶呤的吸收情况。
Br J Cancer. 1980 Oct;42(4):613-5. doi: 10.1038/bjc.1980.286.
3
Clinical pharmacology: drug absorption.临床药理学：药物吸收
Br Med J (Clin Res Ed). 1981 Feb 7;282(6262):462-3. doi: 10.1136/bmj.282.6262.462.
4
Sites of action of amethopterin: intrinsic and acquired drug resistance.氨甲蝶呤的作用位点：内在性和获得性耐药性。
Ann N Y Acad Sci. 1971 Nov 30;186:312-24. doi: 10.1111/j.1749-6632.1971.tb46986.x.
5
Continuous infusion of methotrexate in children with acute leukemia.甲氨蝶呤持续输注治疗儿童急性白血病
Cancer. 1967 Feb;20(2):233-42. doi: 10.1002/1097-0142(1967)20:2<233::aid-cncr2820200209>3.0.co;2-8.
6
Pharmacokinetics of methotrexate.
Clin Pharmacol Ther. 1973 Jul-Aug;14(4):572-9. doi: 10.1002/cpt1973144part1572.
7
Acute lymphocytic leukemia in childhood.儿童急性淋巴细胞白血病
Semin Hematol. 1974 Jan;11(1):25-39.
8
Comparison of serum concentrations of methotrexate after various routes of administration.不同给药途径后甲氨蝶呤血清浓度的比较。
Cancer. 1975 Nov;36(5):1619-24. doi: 10.1002/1097-0142(197511)36:5<1619::aid-cncr2820360514>3.0.co;2-g.
9
Assay of therapeutic doses of methotrexate in body fluids of patients with psoriasis.银屑病患者体液中治疗剂量甲氨蝶呤的测定。
J Invest Dermatol. 1975 Feb;64(2):69-76. doi: 10.1111/1523-1747.ep12510255.
10
Effects of methotrexate on cellular metabolism: some critical elements in the drug-cell interaction.甲氨蝶呤对细胞代谢的影响：药物与细胞相互作用中的一些关键因素。
Cancer Treat Rep. 1977 Jul;61(4):549-58.

Serum profiles of methotrexate after its administration in children with acute lymphoblastic leukaemia.

作者信息

Pinkerton C R, Welshman S G, Bridges J M

出版信息

Br J Cancer. 1982 Feb;45(2):300-3. doi: 10.1038/bjc.1982.47.

DOI:10.1038/bjc.1982.47
PMID:6949608
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2010896/
Abstract
摘要