Fantasia J E, Miller A S, Chen S Y, Foster W B
Oral Surg Oral Med Oral Pathol. 1982 Mar;53(3):273-9. doi: 10.1016/0030-4220(82)90303-6.
Deposition of calcium oxalate in the periodontium with accompanying bone loss and tooth resorption, occurred in a 55-year-old woman on long-term renal dialysis for end-stage renal disease. These deposits were birefringent upon examination with polarized light. Scanning electron microscopy of the deposits revealed clusters of sharply angular oblong and needlelike crystals. Microincineration followed by staining with alizarin red S was positive for calcium oxalate. X-ray diffraction studies of the crystals in the tissue specimen revealed a pattern identical to that of commercially prepared calcium oxalate monohydrate. It is postulated that pre-existing inflammatory periodontal disease may have provided the appropriate milieu for the deposition and precipitation of crystals. These deposits, acting as a foreign body, further intensified the inflammatory response, resulting in extensive alveolar bone loss and external tooth resorption.
一名55岁因终末期肾病接受长期肾透析的女性，其牙周组织出现草酸钙沉积，并伴有骨质流失和牙齿吸收。偏振光检查显示这些沉积物具有双折射性。沉积物的扫描电子显微镜检查显示有尖锐角状的长方形和针状晶体簇。微灰化后用茜素红S染色，草酸钙呈阳性。对组织标本中晶体的X射线衍射研究显示，其模式与市售一水合草酸钙相同。据推测，先前存在的炎症性牙周病可能为晶体的沉积和沉淀提供了适宜的环境。这些沉积物作为异物，进一步加剧了炎症反应，导致广泛的牙槽骨丧失和牙齿外部吸收。
