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1
Localization of an Ia-bearing glomerular cell in the mesangium.系膜中Ia阳性肾小球细胞的定位。
J Cell Biol. 1982 Aug;94(2):483-8. doi: 10.1083/jcb.94.2.483.
2
Characterization of resident glomerular cells in the rat expressing Ia determinants and manifesting genetically restricted interactions with lymphocytes.大鼠中表达Ia决定簇并与淋巴细胞表现出基因限制相互作用的肾小球固有细胞的特征分析
J Clin Invest. 1981 Oct;68(4):920-31. doi: 10.1172/jci110347.
3
Origin of the rat mesangial phagocyte and its expression of the leukocyte common antigen.大鼠系膜吞噬细胞的起源及其白细胞共同抗原的表达。
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4
Disposal of ferritin in the glomerular mesangium of rats.大鼠肾小球系膜中铁蛋白的处理
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Modulation of Ia and leukocyte common antigen expression in rat glomeruli during the course of glomerulonephritis and aminonucleoside nephrosis.大鼠肾小球肾炎和氨基核苷肾病病程中Ia和白细胞共同抗原在大鼠肾小球中的表达调节
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Crossreactions between an I-A allospecificity and the cytoskeleton of glomerular epithelium and of vascular smooth muscle.I-A同种特异性与肾小球上皮细胞及血管平滑肌细胞骨架之间的交叉反应。
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In vivo induction of Ia antigen in resident leukocytes in the normal rat renal glomerulus.正常大鼠肾小球中驻留白细胞Ia抗原的体内诱导
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Clin Immunol Immunopathol. 1989 Nov;53(2 Pt 1):341-5. doi: 10.1016/0090-1229(89)90062-7.
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Human glomerular smooth muscle (mesangial) cells in culture.培养中的人肾小球平滑肌（系膜）细胞。
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Dendritic cells and macrophages in the kidney: a spectrum of good and evil.肾脏中的树突状细胞和巨噬细胞：善恶交织的谱系
Nat Rev Nephrol. 2014 Nov;10(11):625-43. doi: 10.1038/nrneph.2014.170. Epub 2014 Sep 30.
3
The renal mononuclear phagocytic system.肾脏单核吞噬细胞系统。
J Am Soc Nephrol. 2012 Feb;23(2):194-203. doi: 10.1681/ASN.2011070680. Epub 2011 Dec 1.
4
Macrophages and cellular immunity in experimental glomerulonephritis.实验性肾小球肾炎中的巨噬细胞与细胞免疫
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5
Ia expression by vascular endothelium is inducible by activated T cells and by human gamma interferon.血管内皮细胞的Ia表达可被活化的T细胞和人γ干扰素诱导。
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[Biophysicochemical structures of the glomerular filter].[肾小球滤过器的生物物理化学结构]
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Intramesangial passage of mononuclear phagocytes in murine lupus glomerulonephritis.单核吞噬细胞在小鼠狼疮性肾小球肾炎中的系膜内穿行
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8
Identification of lymphohemopoietic cells in the kidneys of normal rats.正常大鼠肾脏中淋巴造血细胞的鉴定。
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Monocytes secrete factors regulating glycosaminoglycan synthesis in mesangial cells in vitro.单核细胞在体外分泌调节系膜细胞中糖胺聚糖合成的因子。
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10
Analysis of T cells and major histocompatibility complex class I and class II mRNA and protein content and distribution in antiglomerular basement membrane disease in the rabbit.兔抗肾小球基底膜病中T细胞及主要组织相容性复合体I类和II类mRNA与蛋白质含量及分布的分析
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本文引用的文献

1
Relations of the centrolobular region of the glomerulus to the juxtaglomerular apparatus.肾小球小叶中心区域与球旁器的关系。
J Ultrastruct Res. 1962 Jun;6:562-78. doi: 10.1016/s0022-5320(62)80010-0.
2
Expression of HLA-ABC and -DR locus antigens on human kidney, endothelial, tubular and glomerular cells.HLA - ABC和 - DR基因座抗原在人肾、内皮、肾小管及肾小球细胞上的表达。
Scand J Immunol. 1980;11(3):303-10. doi: 10.1111/j.1365-3083.1980.tb00238.x.
3
Localization of MHC antigens in long surviving rat renal allografts: probable implication of passenger leukocytes in graft adaptation.
Transplant Proc. 1981 Mar;13(1 Pt 1):95-9.
4
Distribution of endothelial-monocyte and HLA antigens on renal vascular endothelium.内皮单核细胞和HLA抗原在肾血管内皮上的分布。
Transplant Proc. 1981 Mar;13(1 Pt 1):103-7.
5
The glomerular mesangium.肾小球系膜。
Kidney Int. 1980 Feb;17(2):141-54. doi: 10.1038/ki.1980.18.
6
Characterization of resident glomerular cells in the rat expressing Ia determinants and manifesting genetically restricted interactions with lymphocytes.大鼠中表达Ia决定簇并与淋巴细胞表现出基因限制相互作用的肾小球固有细胞的特征分析
J Clin Invest. 1981 Oct;68(4):920-31. doi: 10.1172/jci110347.
7
The regulatory role of macrophages in antigenic stimulation. Part Two: symbiotic relationship between lymphocytes and macrophages.巨噬细胞在抗原刺激中的调节作用。第二部分：淋巴细胞与巨噬细胞之间的共生关系。
Adv Immunol. 1981;31:1-136. doi: 10.1016/s0065-2776(08)60919-0.
8
Expression of Ia in mouse kidney.Ia在小鼠肾脏中的表达。
Transplantation. 1980 Oct;30(4):256-63. doi: 10.1097/00007890-198010000-00004.
9
Contraction of cultured rat glomerular cells of apparent mesangial origin after stimulation with angiotensin II and arginine vasopressin.用血管紧张素II和精氨酸加压素刺激后，源自明显系膜的培养大鼠肾小球细胞的收缩。
J Clin Invest. 1980 Mar;65(3):754-60. doi: 10.1172/JCI109723.
10
Glomerular localization and transport of aggregated proteins in mice.小鼠中聚集蛋白的肾小球定位与转运
Lab Invest. 1967 Jul;17(1):14-29.

系膜中Ia阳性肾小球细胞的定位。

Localization of an Ia-bearing glomerular cell in the mesangium.

作者信息

Schreiner G F, Cotran R S

出版信息

J Cell Biol. 1982 Aug;94(2):483-8. doi: 10.1083/jcb.94.2.483.

DOI:10.1083/jcb.94.2.483
PMID:6955310
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2112893/
Abstract

Using trypsin to render intact, isolated rat glomeruli permeable to antibody, and using an electron microscopic immunoperoxidase technique, we have localized a phagocytic immunologically-relevant cell bearing Ia determinants to the renal mesangium. Thus there are at least two functionally distinct cell types in the renal mesangium: one is a contractile smooth musclelike cell, and the other a phagocytic cell that bears immunologically-relevant surface determinants.

摘要

我们使用胰蛋白酶使完整分离的大鼠肾小球对抗体具有通透性，并采用电子显微镜免疫过氧化物酶技术，将一种带有Ia决定簇的与免疫相关的吞噬细胞定位到肾系膜。因此，肾系膜中至少存在两种功能不同的细胞类型：一种是具有收缩功能的平滑肌样细胞，另一种是带有与免疫相关表面决定簇的吞噬细胞。