系膜中Ia阳性肾小球细胞的定位。
Localization of an Ia-bearing glomerular cell in the mesangium.
作者信息
Schreiner G F, Cotran R S
出版信息
J Cell Biol. 1982 Aug;94(2):483-8. doi: 10.1083/jcb.94.2.483.
Abstract
Using trypsin to render intact, isolated rat glomeruli permeable to antibody, and using an electron microscopic immunoperoxidase technique, we have localized a phagocytic immunologically-relevant cell bearing Ia determinants to the renal mesangium. Thus there are at least two functionally distinct cell types in the renal mesangium: one is a contractile smooth musclelike cell, and the other a phagocytic cell that bears immunologically-relevant surface determinants.
摘要
我们使用胰蛋白酶使完整分离的大鼠肾小球对抗体具有通透性，并采用电子显微镜免疫过氧化物酶技术，将一种带有Ia决定簇的与免疫相关的吞噬细胞定位到肾系膜。因此，肾系膜中至少存在两种功能不同的细胞类型：一种是具有收缩功能的平滑肌样细胞，另一种是带有与免疫相关表面决定簇的吞噬细胞。
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