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股骨远端儿童骨肉瘤的旋转成形术

Rotation-plasty for childhood osteosarcoma of the distal part of the femur.

作者信息

Kotz R, Salzer M

出版信息

J Bone Joint Surg Am. 1982 Sep;64(7):959-69.

PMID:6956578
Abstract

A rotation-plasty procedure was used in four children with osteosarcoma of the distal part of the femur. The results showed that this procedure, combined with en bloc wide excision of the proximal part of the tibia and the distal part of the femur including the knee joint, appears to be an adequate surgical treatment for osteosarcoma of the distal part of the femur in children. None of our patients to date had either clinical or radiographic evidence of local recurrence during follow-up periods of between twenty-seven and fifty-eight months. One patient, however, died of widespread metastatic disease. Despite postoperative adjuvant chemotherapy with high doses of methotrexate, there have been no problems with wound-healing and early fitting of a prosthesis was possible. Because of the success in preventing local recurrence in these four patients, we now generally employ this method in the surgical management of osteosarcoma of the distal part of the femur in children.

摘要

对4例股骨远端骨肉瘤患儿采用了旋转成形术。结果表明,该手术联合整块广泛切除胫骨近端和股骨远端(包括膝关节),似乎是治疗儿童股骨远端骨肉瘤的一种合适的手术方法。在我们的患者中,至今没有1例在27至58个月的随访期内出现局部复发的临床或影像学证据。然而,有1例患者死于广泛转移。尽管术后采用大剂量甲氨蝶呤辅助化疗,但伤口愈合没有问题,且能够早期安装假体。由于这4例患者成功预防了局部复发,我们现在一般采用这种方法治疗儿童股骨远端骨肉瘤。

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