Finklestein S, Benowitz L I, Baldessarini R J, Arana G W, Levine D, Woo E, Bear D, Moya K, Stoll A L
Ann Neurol. 1982 Nov;12(5):463-8. doi: 10.1002/ana.410120509.
Assessments of mood disturbance and "vegetative" (appetite or sleep) disturbance as well as a single-dose dexamethasone suppression test (DST) were carried out in 25 randomly selected stroke patients and in 13 nonstroke control patients hospitalized in a rehabilitation center. Prevalence rates of moderate-to-serve depression of mood and vegetative disturbance were significantly higher in stroke patients than controls (48% and 52% versus 0% and 8%, respectively), as was the prevalence of abnormal DST results (52% versus 8%). Abnormal DST results were associated with the occurrence of moderate to severe mood, appetite, and sleep disturbances among all patients. in 2 stroke patients, repeated DST results paralleled the clinical course. The DST may be useful as an adjunct to the diagnosis and in monitoring the progress of the common and potentially reversible mood and vegetative disturbances occurring after stroke.
对25名随机选取的中风患者以及13名在康复中心住院的非中风对照患者进行了情绪障碍和“植物神经”（食欲或睡眠）障碍评估，以及单剂量地塞米松抑制试验（DST）。中风患者中重度情绪抑郁和植物神经紊乱的患病率显著高于对照组（分别为48%和52%，而对照组为0%和8%），DST结果异常的患病率也是如此（52%对8%）。在所有患者中，DST结果异常与中度至重度情绪、食欲和睡眠障碍的发生有关。在2名中风患者中，重复的DST结果与临床病程平行。DST作为中风后常见且可能可逆的情绪和植物神经紊乱的诊断辅助手段以及监测其进展可能是有用的。
