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副溶血性弧菌侧鞭毛的抗原性:鞭毛中存在两种不同的抗原决定簇。

Antigenicity of lateral flagella of Vibrio parahaemolyticus: existence of two distinct antigenic determinants in a flagellum.

作者信息

Shinoda S, Nakahara N

出版信息

Infect Immun. 1977 Jul;17(1):235-7. doi: 10.1128/iai.17.1.235-237.1977.

DOI:10.1128/iai.17.1.235-237.1977
PMID:69612
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC421106/
Abstract

Cells of Vibrio parahaemolyticus treated with Formalin agglutinated with anti-lateral flagella antiserum. On the basis of agglutination tests, antigens of lateral flagella were divided into three groups. HL1, HL2, and HL3. However, in gel diffusion tests, flagellins prepared from strains belonging to different groups showed a common antigenicity. It is assumed that these results are due to the existence of two distinct antigenic determinants in the lateral flagella. One of them exists on the surfaces of the flagella and is responsible for H-agglutination, and the other exists inside the flagella and is exposed when the flagella are solubilized to flagellin monomers.

摘要

经福尔马林处理的副溶血性弧菌细胞与抗侧鞭毛抗血清发生凝集。基于凝集试验,侧鞭毛抗原分为三组,即HL1、HL2和HL3。然而,在凝胶扩散试验中,来自不同组别的菌株制备的鞭毛蛋白显示出共同的抗原性。推测这些结果是由于侧鞭毛中存在两种不同的抗原决定簇。其中一种存在于鞭毛表面,负责H凝集,另一种存在于鞭毛内部,当鞭毛溶解为鞭毛蛋白单体时暴露出来。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4122/421106/a70d50bb1999/iai00211-0247-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4122/421106/279d9322dfcb/iai00211-0247-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4122/421106/a70d50bb1999/iai00211-0247-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4122/421106/279d9322dfcb/iai00211-0247-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4122/421106/a70d50bb1999/iai00211-0247-b.jpg

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本文引用的文献

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J Bacteriol. 1951 Oct;62(4):377-89. doi: 10.1128/jb.62.4.377-389.1951.
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Antigens of Vibrio parahaemolyticus. I. Preparation of specific antisera to somatic (O) antigen and their application in antigen analysis of Vibrio parahaemolyticus.副溶血性弧菌的抗原。I. 抗体细胞(O)抗原特异性抗血清的制备及其在副溶血性弧菌抗原分析中的应用。
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Taxonomy of marine bacteria: Beneckea parahaemolytica and Beneckea alginolytica.海洋细菌的分类学:副溶血贝内克氏菌和解藻酸贝内克氏菌。
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