Fortner J G, Kim D K, Hopkins L, Barrett M K, Pinsky C M, Day N K
Surg Gynecol Obstet. 1980 Feb;150(2):215-8.
The immune fuction of 41 patients with duct cell adenocarcinoma of the pancreas or carcinoma of the periampullary region was studied by skin testing with 2,4-dinitrocholorobenzene and common microbial antigens, in vitro lymphocyte reactivity to mitogens, T-lymphocyte and B-lymphocyte cell counts and measurements of complement levels. Results show that a great proportion of patients had depressed immune function. Depression is particularly severe in lymphocyte reactivity. Positive response to skin tests with a microbial antigen carries a slightly better prognosis. The complement level is usually normal or elevated. Correlation between immune function, prognosis and tumor resectability in individual patients is generally poor.
通过用2,4 - 二硝基氯苯和常见微生物抗原进行皮肤试验、体外淋巴细胞对有丝分裂原的反应性、T淋巴细胞和B淋巴细胞计数以及补体水平测定，对41例胰腺导管细胞腺癌或壶腹周围癌患者的免疫功能进行了研究。结果显示，很大一部分患者的免疫功能低下。淋巴细胞反应性的降低尤为严重。对微生物抗原皮肤试验呈阳性反应的患者预后略好。补体水平通常正常或升高。个体患者的免疫功能、预后与肿瘤可切除性之间的相关性一般较差。
