Lubach D, Marghescu S, Bialasiewicz A A
Fortschr Med. 1980 Sep 18;98(35):1343-7.
Immune abnormalities in psoriasis vulgaris are described. Anti-stratum corneum antibodies deposited with C3 have been found in patients with psoriasis. A lot of other immune abnormalities identified in psoriasis: increased serum IgG and IgA levels, lowered DNCB-sensitization, alteration in polymorphnuclear leukocytes (PMN) function, decreased number of T cells, lack of response to concanavalin A (ConA) and an increase in the polyclonal B cell activation. the authors believe that the immunoregulatory defect is due to the disorder of the skin.
寻常型银屑病的免疫异常已被描述。在银屑病患者中发现了与C3沉积的抗角质层抗体。在银屑病中还发现了许多其他免疫异常：血清IgG和IgA水平升高、二硝基氯苯致敏性降低、多形核白细胞（PMN）功能改变、T细胞数量减少、对刀豆蛋白A（ConA）无反应以及多克隆B细胞活化增加。作者认为免疫调节缺陷是由于皮肤紊乱所致。
