Hsieh K H
Ann Allergy. 1980 Feb;44(2):91-4.
The effects of cyclophosphamide (200 microgram/ml), levamisole (1 microgram/ml) and Concanavalin A (10 microgram/ml) on the in vitro IgE biosynthesis of lymphocytes from 2 allergic children and six healthy adults were studied. The capability of the IgE biosynthesis was enhanced by cyclophosphamide in nine allergic children, suppressed by levamisole in three and not changed by Concanavalin A. The three patients who showed in vitro suppressed IgE synthesis by levamisole had been treated with levamisole for more than three months but only one revealed decreased serum IgE.
研究了环磷酰胺（200微克/毫升）、左旋咪唑（1微克/毫升）和刀豆球蛋白A（10微克/毫升）对2名过敏儿童和6名健康成年人淋巴细胞体外IgE生物合成的影响。环磷酰胺增强了9名过敏儿童的IgE生物合成能力，左旋咪唑抑制了3名患者的该能力，刀豆球蛋白A对其无影响。3名体外显示左旋咪唑抑制IgE合成的患者接受左旋咪唑治疗已超过3个月，但只有1名患者血清IgE降低。
