Areskog M, Tibbling L, Wranne B
Acta Med Scand. 1980;207(5):403-5. doi: 10.1111/j.0954-6820.1980.tb09746.x.
The incidence of oesophageal dysfunction (OD) is higher in patients with coronary heart disease (CHD) than in a population sample. The hypothesis was raised that this finding is the result of a cardio-oesophageal reflex in which afferent pain impulses from the heart trigger dysfunction in the oesophagus. Twenty-three patients with CHD were examined before and 14+/-5(S.D.) months after coronary bypass surgery. Total relief of angina pectoris was attained in 6 patients and improvement in 16. One patient deteriorated. The incidence of OD was 52% before operation and 65% at the follow-up investigation (no significant difference). Symptoms related to the oesophagus, other than chest pain, were as frequent before as after operation. The findings do not support the contention that OD in patients with CHD is caused by a cardio-oesophageal reflex.
冠心病(CHD)患者食管功能障碍(OD)的发生率高于人群样本。有人提出假说,认为这一发现是心-食管反射的结果,即来自心脏的传入性疼痛冲动触发食管功能障碍。对23例冠心病患者在冠状动脉搭桥手术前及术后14±5(标准差)个月进行了检查。6例患者心绞痛完全缓解,16例有所改善。1例病情恶化。术前OD发生率为52%,随访调查时为65%(无显著差异)。除胸痛外,与食管相关的症状在术前和术后一样常见。这些发现不支持冠心病患者的OD是由心-食管反射引起的这一论点。