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一名大脑半球切除术患者的动眼和眼前庭功能

Oculomotor and oculovestibular functions in a hemispherectomy patient.

作者信息

Estañol B, Romero R, Sáenz de Viteri M, Mateos J H, Corvera J

出版信息

Arch Neurol. 1980 Jun;37(6):365-8. doi: 10.1001/archneur.1980.00500550067009.

DOI:10.1001/archneur.1980.00500550067009
PMID:6966922
Abstract

Oculomotor and oculovestibular functions in a patient who had undergone a left hemispherectomy were examined under a variety of visual and vestibular stimuli. The main findings were an inability to hold left eccentric gaze, resulting in gaze-evoked nystagmus to that side; inaccurate saccades to the right; defective smooth pursuit to the left; asymmetrical vestibulo-ocular responses (VOR) in the dark due to the interaction of the VOR with the "spasticity of conjugate gaze", decreased gain of the visuo-vestibulo-ocular reflexes to both sides, more marked to the right, when rotated fixating on a stationary wall target or the environment, due to abnormal smooth and optokinetic systems; and failure to inhibit the VOR when rotated to the left with visual fixation.

摘要

对一名接受了左侧大脑半球切除术的患者,在多种视觉和前庭刺激下检查了其动眼和眼前庭功能。主要发现包括:无法维持左侧偏心注视,导致向该侧出现凝视诱发的眼球震颤;向右的扫视不准确;向左的平稳跟踪存在缺陷;由于前庭眼反射(VOR)与“共轭凝视痉挛”的相互作用,在黑暗中前庭眼反应不对称;当注视固定在静止的墙壁目标或环境上旋转时,双侧视-前庭-眼反射的增益降低,右侧更明显,这是由于平稳和视动系统异常所致;以及在视觉固定状态下向左旋转时无法抑制前庭眼反射。

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引用本文的文献

1
Interhemispherically dynamic representation of an eye movement-related activity in mouse frontal cortex.在小鼠额皮质中,眼球运动相关活动的半球间动态表现。
Elife. 2019 Nov 5;8:e50855. doi: 10.7554/eLife.50855.
2
Saccades to the seeing visual hemifield in hemidecorticate patients exhibit task-dependent reaction times and hypometria.半脑皮质切除患者向可见视野半侧的扫视运动表现出任务依赖性反应时间和运动幅度减小。
Exp Brain Res. 2007 Sep;182(1):11-25. doi: 10.1007/s00221-007-0969-1. Epub 2007 May 22.
3
Directional preponderance in human optokinetic nystagmus.
Exp Brain Res. 1986;63(2):387-94. doi: 10.1007/BF00236857.
4
Effects of posterior parietal lesions (area 7) on VOR in monkeys.猴子顶叶后部(7区)病变对前庭眼反射的影响。
Exp Brain Res. 1986;62(3):654-8. doi: 10.1007/BF00236046.