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[Effect of exposure to stress on the role of T- and B-lymphocytes in the response of the hematopoietic system].

作者信息

Gorizontov P D, Fedotova M I, Belousova O I, Khaitov R M, Chermeneva L I

出版信息

Biull Eksp Biol Med. 1980 Apr;89(4):415-7.

PMID:6966945
Abstract

Cellular composition of the bone marrow, spleen and peripheral blood was studied after 6-hour immobilization on the back in experiments on 4 groups of (CBAxC57BL)F1 mice with varying degree of T lymphocyte deficiency (thymectomy, sham thymectomy, administration of antilymphocytic serum, B mice). The evidence obtained shows that the "lymphoid peak" recorded in the bone marrow during stress is likely to be formed at the expense of T and B lymphocyte migration from the peripheral lymphoid organs. The data have been also obtained, indicating that T lymphocytes migrating to the bone marrow during the first 6-9 hours after the exposure to stress may participate in granulocytopoiesis activation.

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