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食管压迫疗法治疗静脉曲张出血。十年进展报告。

Esophageal tamponade in the treatment of bleeding varices. A decadel progress report.

作者信息

Chojkier M, Conn H O

出版信息

Dig Dis Sci. 1980 Apr;25(4):267-72. doi: 10.1007/BF01308516.

Abstract

Previous reports from this hospital in 1958 and 1967 have revealed that esophageal tamponade is a relatively dangerous type of treatment. Other investigators have been able to avoid many of the hazards of this technique. We have again assessed our results in 50 episodes of esophageal tamponade in bleeding esophageal varices in 39 patinets. Thirty-seven had alcoholic cirrhosis, one Wilson's disease, and one portal vein thrombosis. The diagnosis of variceal hemorrhage was established by endoscopy or angiography in virtually all. The great majority (86%) had had unsuccessful infusions of vasopressin previously. The Sengstaken-Blakemore tube (SBT) was used in 41 and the Linton tube (LT) in nine. Hemorrhage was controlled for at least 24 consecutive hours in 20 episodes (40%). Ninety percent of the patients died. Rupture of the esophagus following inflation of the gastric balloon in the esophagus caused three deaths (8%). Major nonfatal complications such as aspiration pneumonia occurred on five other occasions. Although the complications of esophageal tamponade were greatly reduced from our previous series, the efficacy of esophageal tamponade also decreased. There were no significant differences in the efficacy or complications of the SBT and LT. The high mortality and complication rates are still discouraging. We believe that the role of esophageal tamponade in the treatment of hemorrhage from varices is a secondary one.

摘要

本院1958年和1967年的既往报告显示,食管压迫止血是一种相对危险的治疗方式。其他研究者已能够避免该技术的许多风险。我们再次评估了39例患者50次食管压迫止血治疗食管静脉曲张出血的结果。其中37例为酒精性肝硬化,1例为威尔逊病,1例为门静脉血栓形成。几乎所有患者的曲张静脉出血诊断均通过内镜检查或血管造影确定。绝大多数(86%)患者此前使用血管加压素输注治疗失败。41例使用了森斯塔肯-布莱克莫尔管(SBT),9例使用了林顿管(LT)。20次(40%)出血得到至少连续24小时的控制。90%的患者死亡。食管内胃气囊充气后食管破裂导致3例死亡(8%)。另外还有5例发生了诸如吸入性肺炎等严重非致命并发症。尽管与我们之前的系列研究相比,食管压迫止血的并发症大幅减少,但其疗效也降低了。SBT和LT在疗效或并发症方面无显著差异。高死亡率和并发症发生率仍然令人沮丧。我们认为食管压迫止血在治疗静脉曲张出血中起次要作用。

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