Watson R L, Langford H G, Abernethy J, Barnes T Y, Watson M J
Hypertension. 1980 Jul-Aug;2(4 Pt 2):93-8.
Results of blood pressures (BP) and urinary electrolyte excretion studies are reported among several groups of adolescent and young adult females, both black and white, who were initially examined in high school and restudied at home 3--4 years later. Pooling of the data from the several cross-sectional studies (n = 662) revealed a weak but statistically significant positive correlation systolic blood pressure (SBP) and the urinary sodium (Na) excretion rate. Three of four correlations between SBP and potassium (K) were of an inverse nature. Although not statistically significant in their own right, when coupled with the Na/K excretion ratio, which was significantly associated with SBP, a moderating role for K is suggested. The urinary Na, K, and creatinine (Cr) excretion rates were highly intercorrelated and were correlated with weight. As measured by R2 in a stepwise regression analysis, weight contributed approximately 3% to the BP variance, and the urinary electrolytes accounted for approximately 2% of the SBP variance. Statistically significant partial correlation coefficients between SBP and Na, and Na/K, remained after adjusting for body weight.
报告了几组青春期及年轻成年女性（包括黑人和白人）的血压（BP）和尿电解质排泄研究结果，这些女性最初在高中接受检查，并在3 - 4年后在家中再次接受研究。汇总来自几项横断面研究（n = 662）的数据显示，收缩压（SBP）与尿钠（Na）排泄率之间存在微弱但具有统计学意义的正相关。SBP与钾（K）之间的四个相关性中有三个呈负相关。尽管钾本身在统计学上不显著，但与与SBP显著相关的钠/钾排泄率相结合时，提示钾具有调节作用。尿钠、钾和肌酐（Cr）排泄率高度相互关联且与体重相关。在逐步回归分析中，以R2衡量，体重对血压方差的贡献约为3%，尿电解质约占收缩压方差的2%。在调整体重后，SBP与钠以及钠/钾之间的统计学显著偏相关系数仍然存在。
