Eaton M L
Am J Hosp Pharm. 1978 Sep;35(9):1099-102.
A case of chronic hypervitaminosis A in a 51-year-old female is discussed. The patient was ingesting 27,500--35,000 international units of vitamin A daily for 30 years. The patient displayed the classic symptoms of the disease, including skin and hair changes, esophageal varices and extensive liver disease. Vitamin A products were discontinued and the patient's dietary intake of the vitamin was minimized. Previous reports and studies of hypervitaminosis A are reviewed. Social factors causing increased consumption of vitamin A and regulations governing the sale of vitamin A are discussed. By being aware of the factors influencing vitamin A consumption, hypervitaminosis A can be detected and prevented more readily.
讨论了一例51岁女性慢性维生素A过多症的病例。该患者连续30年每日摄入27,500 - 35,000国际单位的维生素A。患者表现出该疾病的典型症状,包括皮肤和毛发变化、食管静脉曲张以及广泛的肝脏疾病。停用了维生素A产品,并尽量减少患者饮食中维生素A的摄入量。回顾了先前关于维生素A过多症的报告和研究。讨论了导致维生素A摄入量增加的社会因素以及维生素A销售的管理规定。通过了解影响维生素A摄入的因素,可以更容易地检测和预防维生素A过多症。