Tikhonova N T, Khrometskaia T M, Mamaeva T A, Azarova S A, Livanova L V
Zh Mikrobiol Epidemiol Immunobiol. 1980 Jul(7):58-63.
The comparative study of the humoral and cellular characteristics of antimeasles immunity in children immunized with live measles vaccine Ji-16, and in children having had measles revealed that both "wild" and vaccine strains of measles virus induced similar changes in the organism of the child: the synthesis of specific antibodies belonging to different physico-chemical classes, changes in the content of different serum immunoglobulins and the suppression of the blastogenic response of peripheral blood lymphoyctes to phitohemagglutinins. The changes suggest that both T- and B-lymphocytes took part in the formation of antimeasles immunity, but all these processes were more pronounced during the formation of postinfection immunity.
对接种吉-16 株麻疹活疫苗的儿童和患过麻疹的儿童的抗麻疹免疫的体液和细胞特性进行的比较研究表明,麻疹病毒的“野生”株和疫苗株在儿童机体中引起了相似的变化:合成了属于不同理化类别的特异性抗体,不同血清免疫球蛋白含量发生变化,外周血淋巴细胞对植物血凝素的 blastogenic 反应受到抑制。这些变化表明,T 淋巴细胞和 B 淋巴细胞都参与了抗麻疹免疫的形成,但所有这些过程在感染后免疫形成过程中更为明显。