前列腺素对小鼠红细胞花环形成人淋巴细胞的影响。
Effect of prostaglandins on mouse erythrocyte rosette-forming human lymphocytes.
作者信息
Misefari A, Venza-Teti D, LaVia M F
出版信息
Immunopharmacology. 1980 Apr;2(2):109-15. doi: 10.1016/0162-3109(80)90003-x.
PMID:6969242
Abstract
Prostaglandins (PGs) E2 and F2 alpha, preincubated with human lymphocytes for short periods of time inhibit mouse erythrocyte rosette formation. The presence of calcium ions does not influence this effect, which is dose-dependent and relatively temperature-independent. These observations indicate the PG treatment of lymphocytes may be useful to distinguish a subclass of IgM-bearing mouse erythrocyte rosette-forming B lymphocytes, which is sensible to the modulating effect of Pgs.
摘要
前列腺素（PGs）E2和F2α，与人淋巴细胞短期预孵育后，会抑制小鼠红细胞玫瑰花结的形成。钙离子的存在不影响这种效应，该效应呈剂量依赖性且相对不依赖温度。这些观察结果表明，用PG处理淋巴细胞可能有助于区分一类对PG调节作用敏感的、带有IgM的小鼠红细胞玫瑰花结形成B淋巴细胞亚群。
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