前列腺素E2和F2α对正常淋巴细胞E花环形成活性影响的体外研究。
An invitro study on the effect of prostaglandin E2 and F2 alpha on E-rosette forming activity of normal lymphocytes.
作者信息
Erten U, Emre T, Cavdar A O, Türker R K
出版信息
Prostaglandins Med. 1980 Oct;5(4):255-8. doi: 10.1016/0161-4630(80)90027-0.
The effects of PGE2 and F2 alpha have been studied on E-rosette forming activity of normal human peripheral blood lymphocytes. Addition of both PGs into the incubation medium caused a significant and concentration - dependent inhibition of E-rosette formation. The minimum effective concentration of both PGs was found to be 10(-9) M and complete inhibition was obtained when the concentration was increased to 10(-7) M. Possible mechanisms of the action of PGs on E-rosette formation are discussed.
已对前列腺素E2（PGE2）和前列腺素F2α（F2α）对正常人外周血淋巴细胞E花环形成活性的影响进行了研究。将这两种前列腺素添加到孵育培养基中会导致E花环形成受到显著的浓度依赖性抑制。发现这两种前列腺素的最小有效浓度为10^(-9)M，当浓度增加到10^(-7)M时可获得完全抑制。文中讨论了前列腺素对E花环形成作用的可能机制。
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