Onody C, Bátory G, Patrányi G G
Thymus. 1980 Jan;1(4-5):205-13.
In the course of family investigations a linear age-dependent decrease of reactivity against pooled allogeneic lymphocytes was found between 20 and 70 yr of age. This decreasing tendency was ascertained also by the investigation of unrelated people of a more advanced age. In the elderly, maximal transformation values in PHA stimulation investigated at different PHA doses showed a similar degree of reduction as allogeneic reactivity, and a good correlation between the two parameters of T-lymphocyte function has been found.
在家族调查过程中，发现20至70岁之间针对混合异体淋巴细胞的反应性随年龄呈线性下降。对年龄更大的无关个体进行调查也证实了这种下降趋势。在老年人中，不同PHA剂量下PHA刺激的最大转化值显示出与异体反应性相似程度的降低，并且发现T淋巴细胞功能的这两个参数之间具有良好的相关性。
