小鼠肠道黏膜中特异性细胞毒性T细胞的早期出现。
The early appearance of specific cytotoxic T cells in murine gut mucosa.
作者信息
Davies M D, Parrott D M
出版信息
Clin Exp Immunol. 1980 Nov;42(2):273-9.
Abstract
Using a new technique for isolating lymphoid cells from the lamina propria of murine small intestine, we have examined the appearance of specific cytotoxic T cells in the gut following intraperitoneal immunization with an allogenic tumour. Specific cytotoxic T cells appeared in the lamina propria at a time when there are very few cytotoxic lymphocytes in any of the organized lymphoid tissues. Greater levels of cytotoxicity were found in the gut compared with any other site for at least 3 weeks following a single injection of tumour cells.
摘要
利用一种从鼠小肠固有层分离淋巴细胞的新技术，我们研究了同种异体肿瘤腹腔免疫后肠道中特异性细胞毒性T细胞的出现情况。当任何有组织的淋巴组织中细胞毒性淋巴细胞很少时，固有层中出现了特异性细胞毒性T细胞。单次注射肿瘤细胞后至少3周内，肠道中的细胞毒性水平高于其他任何部位。
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