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小鼠肠道黏膜中特异性细胞毒性T细胞的早期出现。

The early appearance of specific cytotoxic T cells in murine gut mucosa.

作者信息

Davies M D, Parrott D M

出版信息

Clin Exp Immunol. 1980 Nov;42(2):273-9.

PMID:6970637
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1537107/
Abstract

Using a new technique for isolating lymphoid cells from the lamina propria of murine small intestine, we have examined the appearance of specific cytotoxic T cells in the gut following intraperitoneal immunization with an allogenic tumour. Specific cytotoxic T cells appeared in the lamina propria at a time when there are very few cytotoxic lymphocytes in any of the organized lymphoid tissues. Greater levels of cytotoxicity were found in the gut compared with any other site for at least 3 weeks following a single injection of tumour cells.

摘要

利用一种从鼠小肠固有层分离淋巴细胞的新技术，我们研究了同种异体肿瘤腹腔免疫后肠道中特异性细胞毒性T细胞的出现情况。当任何有组织的淋巴组织中细胞毒性淋巴细胞很少时，固有层中出现了特异性细胞毒性T细胞。单次注射肿瘤细胞后至少3周内，肠道中的细胞毒性水平高于其他任何部位。

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The early appearance of specific cytotoxic T cells in murine gut mucosa.小鼠肠道黏膜中特异性细胞毒性T细胞的早期出现。
Clin Exp Immunol. 1980 Nov;42(2):273-9.
2
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本文引用的文献

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Patterns of lymphatic drainage in the adult laboratory rat.成年实验大鼠的淋巴引流模式。
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Studies of allograft immunity in mice. I. Induction, development and in vitro assay of cellular immunity.小鼠同种异体移植免疫研究。I. 细胞免疫的诱导、发展及体外检测
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A rapid method for the isolation of functional thymus-derived murine lymphocytes.一种分离功能性胸腺来源的小鼠淋巴细胞的快速方法。
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Primary tumours of the small intestine.小肠原发性肿瘤
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A simplified 51Cr-release assay for killer cells.一种用于杀伤细胞的简化51铬释放试验。
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6
Antibody-dependent cell-mediated cytotoxicity due to a "null" lymphoid cell.由“无标记”淋巴细胞引起的抗体依赖性细胞介导的细胞毒性。
Nat New Biol. 1973 Mar 28;242(117):111-3. doi: 10.1038/newbio242111a0.
7
"Natural" killer cells in the mouse. I. Cytotoxic cells with specificity for mouse Moloney leukemia cells. Specificity and distribution according to genotype.小鼠中的“天然”杀伤细胞。I. 对小鼠莫洛尼白血病细胞具有特异性的细胞毒性细胞。根据基因型的特异性和分布。
Eur J Immunol. 1975 Feb;5(2):112-7. doi: 10.1002/eji.1830050208.
8
Killer cells: a functional comparison between natural, immune T-cell and antibody-dependent in vitro systems.杀伤细胞：天然杀伤细胞、免疫T细胞与抗体依赖体外系统之间的功能比较
J Exp Med. 1976 Apr 1;143(4):772-80. doi: 10.1084/jem.143.4.772.
9
Studies on the induction and expression of T cell-mediated immunity. V. Lectin-induced nonspecific cell-mediated cytotoxicity by alloimmune lymphocytes.T细胞介导免疫的诱导与表达研究。V. 同种异体免疫淋巴细胞的凝集素诱导非特异性细胞介导细胞毒性
Transplantation. 1976 Feb;21(2):94-102. doi: 10.1097/00007890-197602000-00002.
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Natural cytotoxic reactivity of mouse lymphoid cells against syngeneic and allogeneic tumors. II. Characterization of effector cells.小鼠淋巴细胞对同基因和异基因肿瘤的天然细胞毒性反应。II. 效应细胞的特性
Int J Cancer. 1975 Aug 15;16(2):230-9. doi: 10.1002/ijc.2910160205.