在低丙种球蛋白血症患者淋巴细胞研究中，用甲醛处理的细菌作为选择性B细胞有丝分裂原。
Formalin-treated bacteria as selective B cell mitogens in the study of lymphocytes from patients with hypogammaglobulinaemia.
作者信息
Banck G, Forsgren A
出版信息
Clin Exp Immunol. 1980 Dec;42(3):530-4.
Abstract
Staphylococcus aureus strain Cowan I, Haemophilus influenzae, and Branhamella catarrhalis that stimulate human B lymphocytes, but not T lymphocytes, were used to study the B lymphocyte function in patients with hypogammaglobulinaemia. Lymphocytes from two patients with no circulating B cells were not stimulated to increased DNA synthesis by these bacterial mitogens. The lymphocytes of six patients with hypogammaglobulinaemia and normal numbers of circulating B cells responded to the bacterial mitogens but in five patients the response was decreased in comparison with healthy controls.
摘要
用能刺激人B淋巴细胞而不刺激T淋巴细胞的金黄色葡萄球菌考恩I株、流感嗜血杆菌和卡他布兰汉菌，来研究低丙种球蛋白血症患者的B淋巴细胞功能。两名无循环B细胞患者的淋巴细胞，未被这些细菌促有丝分裂原刺激而增加DNA合成。六名低丙种球蛋白血症且循环B细胞数量正常患者的淋巴细胞对细菌促有丝分裂原产生反应，但与健康对照相比，五名患者的反应减弱。
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引用本文的文献
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Formalin-treated bacteria as selective B cell mitogens: results in primary and acquired immunodeficiencies.经福尔马林处理的细菌作为选择性B细胞有丝分裂原：导致原发性和获得性免疫缺陷。
Clin Exp Immunol. 1981 Aug;45(2):393-8.
本文引用的文献
1
Clinical, serologic and leukocyte function studies on patients with idiopathic "acquired" agammaglobulinemia and their families.
Am J Med. 1970 Jan;48(1):48-53. doi: 10.1016/0002-9343(70)90097-5.
2
Immunochemical quantitation of antigens by single radial immunodiffusion.通过单向辐射免疫扩散法对抗原进行免疫化学定量。
Immunochemistry. 1965 Sep;2(3):235-54. doi: 10.1016/0019-2791(65)90004-2.
3
Genetic control of the immune response. The effect of thymectomy on the primary and secondary antibody response of mice to poly-L(tyr, glu)-poly-D, L-ala--poly-L-lys.免疫反应的遗传控制。胸腺切除对小鼠针对聚-L（酪氨酰、谷氨酰）-聚-D，L-丙氨酰-聚-L-赖氨酸的初次和二次抗体反应的影响。
J Exp Med. 1972 Jan;135(1):126-35. doi: 10.1084/jem.135.1.126.
4
Identification and function of T cells in the peripheral blood of patients with hypogammaglobulinaemia.低丙种球蛋白血症患者外周血中T细胞的鉴定及功能
Clin Exp Immunol. 1974 Dec;18(4):499-504.
5
Role of suppressor T cells in pathogenesis of common variable hypogammaglobulinaemia.抑制性T细胞在常见变异型低丙种球蛋白血症发病机制中的作用。
Lancet. 1974 Sep 14;2(7881):609-13. doi: 10.1016/s0140-6736(74)91940-0.
6
Surface markers on human T and B lymphocytes. I. A large population of lymphocytes forming nonimmune rosettes with sheep red blood cells.人类T和B淋巴细胞的表面标志物。I. 大量与绵羊红细胞形成非免疫性玫瑰花结的淋巴细胞。
J Exp Med. 1972 Aug 1;136(2):207-15. doi: 10.1084/jem.136.2.207.
7
Functional analysis of murine and human B lymphocyte subsets.小鼠和人类B淋巴细胞亚群的功能分析。
Transplant Rev. 1975;24:177-236. doi: 10.1111/j.1600-065x.1975.tb00169.x.
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A human T-independent B lymphocyte mitogen extracted from Nocardia opaca.一种从暗产色诺卡氏菌中提取的人非T细胞依赖性B淋巴细胞促有丝分裂原。
J Immunol. 1976 Nov;117(5 Pt 1):1434-9.
9
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Eur J Immunol. 1976 Mar;6(3):207-13. doi: 10.1002/eji.1830060312.
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Br Med J. 1977 Mar 5;1(6061):614. doi: 10.1136/bmj.1.6061.614.
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