在低丙种球蛋白血症患者淋巴细胞研究中，用甲醛处理的细菌作为选择性B细胞有丝分裂原。
Formalin-treated bacteria as selective B cell mitogens in the study of lymphocytes from patients with hypogammaglobulinaemia.
作者信息
Banck G, Forsgren A
出版信息
Clin Exp Immunol. 1980 Dec;42(3):530-4.
Abstract
Staphylococcus aureus strain Cowan I, Haemophilus influenzae, and Branhamella catarrhalis that stimulate human B lymphocytes, but not T lymphocytes, were used to study the B lymphocyte function in patients with hypogammaglobulinaemia. Lymphocytes from two patients with no circulating B cells were not stimulated to increased DNA synthesis by these bacterial mitogens. The lymphocytes of six patients with hypogammaglobulinaemia and normal numbers of circulating B cells responded to the bacterial mitogens but in five patients the response was decreased in comparison with healthy controls.
摘要
用能刺激人B淋巴细胞而不刺激T淋巴细胞的金黄色葡萄球菌考恩I株、流感嗜血杆菌和卡他布兰汉菌，来研究低丙种球蛋白血症患者的B淋巴细胞功能。两名无循环B细胞患者的淋巴细胞，未被这些细菌促有丝分裂原刺激而增加DNA合成。六名低丙种球蛋白血症且循环B细胞数量正常患者的淋巴细胞对细菌促有丝分裂原产生反应，但与健康对照相比，五名患者的反应减弱。
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引用本文的文献
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Formalin-treated bacteria as selective B cell mitogens: results in primary and acquired immunodeficiencies.经福尔马林处理的细菌作为选择性B细胞有丝分裂原：导致原发性和获得性免疫缺陷。
Clin Exp Immunol. 1981 Aug;45(2):393-8.
本文引用的文献
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Clinical, serologic and leukocyte function studies on patients with idiopathic "acquired" agammaglobulinemia and their families.对特发性“获得性”无丙种球蛋白血症患者及其家族进行的临床、血清学和白细胞功能研究。
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