Mulley J C, Bryant G D, Sutherland G R
Ann Genet. 1980;23(4):198-200.
Exclusion mapping was applied to individuals with monosomic segments defined by chromosomal banding. A range of genetic markers and blood groups was determined resulting in new exclusions for unassigned markers at the following segments : (3)(p25 leads to pter) - JK, GPT, PI ; (4)(127 leads to 31) - MNS, JK, PI, C3, F13A, F13B ; (7))q22) - LU, F13A ; (12)(p12) - MNS ; (12)(p13) and (15)(q15) - GPT, C3 ; (12) (pter) and (19)(p or qter) - MNS, GPT, PI ; and (18)(q21 leads to 23) - MNS, JK, F13A. These exclusions may be useful for narrowing the regional localisations of any genetic markers subsequently assigned to the chromosome involved in the exclusion. No new gene assignments were made from cases where family data was available.
排除定位法应用于具有通过染色体显带定义的单体片段的个体。确定了一系列遗传标记和血型，从而为以下片段上未定位的标记产生了新的排除结果：(3)(p25至pter) - JK、GPT、PI；(4)(127至31) - MNS、JK、PI、C3、F13A、F13B；(7)(q22) - LU、F13A；(12)(p12) - MNS；(12)(p13)和(15)(q15) - GPT、C3；(12)(pter)和(19)(p或qter) - MNS、GPT、PI；以及(18)(q21至23) - MNS、JK、F13A。这些排除结果可能有助于缩小随后分配给排除所涉及染色体的任何遗传标记的区域定位范围。对于有家族数据的病例，未进行新的基因定位。
