Schaefer S D, Wright C G, Post J D, Frenkel E P
Cancer. 1981 Mar 1;47(5):857-9. doi: 10.1002/1097-0142(19810301)47:5<857::aid-cncr2820470508>3.0.co;2-m.
Cis-diamminedichloroplatinum has been proven to be an effective neoplastic agent. Nephrotoxicity and ototoxicity are two prominent side effects of this drug. Investigation of ototoxicity has been limited to auditory function. This report details the first known case of vestibular toxicity following platinum therapy. In addition, a prospective vestibular testing program is reported.
顺二氯二氨铂已被证明是一种有效的抗肿瘤药物。肾毒性和耳毒性是该药物的两个突出副作用。对耳毒性的研究仅限于听觉功能。本报告详细介绍了首例已知的铂类治疗后前庭毒性病例。此外，还报告了一项前瞻性前庭测试计划。
