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铯对乙酰胆碱诱导电流的影响。在蛙心房中,乙酰胆碱会使内向整流钾电流(IK1)增加吗?

Effects of Cs on acetylcholine induced current. Is ik1 increased by acetylcholine in frog atrium?

作者信息

Ojeda C, Rougier O, Tourneur Y

出版信息

Pflugers Arch. 1981 Jul;391(1):57-9. doi: 10.1007/BF00580695.

Abstract

1.20 mM Cs+ ions reduce background current and decrease drastically the K+ depletion process, probably as a consequence of the reduction of iK1. The background current-voltage relationship becomes linear. 2. 20 mM Cs+ ions completely abolish the current induced by acetylcholine. 3. The possibility that the K+ current induced by acetylcholine is due to an increase of iK1 is discussed.

摘要
  1. 20毫摩尔的铯离子可降低背景电流,并显著减缓钾离子耗尽过程,这可能是内向整流钾电流(iK1)减小的结果。背景电流与电压的关系变为线性。2. 20毫摩尔的铯离子可完全消除乙酰胆碱诱导的电流。3. 文中讨论了乙酰胆碱诱导的钾电流是由于内向整流钾电流增加所致的可能性。

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