Urowitz M B, Gladman D D, Minta J O
J Rheumatol. 1981 Sep-Oct;8(5):741-6.
A 40-year-old female with systemic lupus erythematosus was found to be totally deficient in the 4th component of complement and to be lacking in Chido and Rodgers blood group substances on red cells and in plasma. Family studies were suggestive of a linkage of the C4 deficiency with an HLA haplotype. C2 in the patient's serum was 50% of normal but other complement components and alternative pathway functions were normal. Chemotactic and opsonic activities in the patient's serum were diminished.
一名40岁的系统性红斑狼疮女性患者被发现完全缺乏补体第四成分，其红细胞和血浆中缺乏奇多（Chido）和罗杰斯（Rodgers）血型物质。家族研究提示C4缺乏与一种HLA单倍型存在连锁关系。该患者血清中的C2为正常水平的50%，但其他补体成分和替代途径功能正常。患者血清中的趋化活性和调理活性降低。
