Hau J, Westergaard J G, Svendsen P, Bach A, Teisner B
J Reprod Immunol. 1981 Dec;3(6):341-9. doi: 10.1016/0165-0378(81)90050-4.
Immunological cross-reaction between human pregnancy zone protein (PZP, SP-3, alpha 2-PAG) and pregnancy-associated murine protein-1 (PAMP-1) was demonstrated by countercurrent line immunoelectrophoresis using antibodies against the proteins raised in hens. The levels of PZP and PAMP-1 were measured during pregnancy and found to be very similar in the first half of pregnancy. Both proteins were found to be heterogeneous and separable according to surface properties. It is suggested that the murine PAMP-1 can be used to study the physiology of human PZP.
利用针对在母鸡体内产生的这些蛋白质的抗体，通过对流线免疫电泳证明了人妊娠区蛋白（PZP、SP-3、α2-PAG）与妊娠相关小鼠蛋白-1（PAMP-1）之间的免疫交叉反应。在妊娠期间测量了PZP和PAMP-1的水平，发现在妊娠的前半期二者非常相似。根据表面性质发现这两种蛋白质都是异质的且可分离。有人提出，小鼠PAMP-1可用于研究人PZP的生理学。
