Yee R D, Baloh R W, Honrubia V
Ophthalmology. 1981 Oct;88(10):1010-8. doi: 10.1016/s0161-6420(81)80029-2.
Eye movements were studied quantitatively using electro-oculography in seven patients with rod monochromacy. Attention was given to eye movement abnormalities that could help to differentiate rod monochromacy from other forms of congenital nystagmus. Horizontal nystagmus in center gaze had pendular and jerk waveforms with much lower amplitude than that in patients with other forms of congenital nystagmus and visual acuity of 20/200-20/400. Slow build-up of slow component velocity over many seconds and directional asymmetry of optokinetic nystagmus (OKN) were observed during monocular optokinetic stimulation. The directional asymmetry of OKN was characterized by a higher OKN gain (eye velocity/OKN drum velocity) during rotation of the OKN drum in the temporal-to-nasal direction in the visual field, than that during drum rotation in the nasal-to temporal direction. Similar directional asymmetry and slow build-up are found in afoveate animals, such as the rabbit, during monocular optokinetic stimulation, but are not found in normal human subjects or in patients with other forms of congenital nystagmus.
利用眼电图对7名视杆单色视患者的眼球运动进行了定量研究。重点关注有助于将视杆单色视与其他形式的先天性眼球震颤区分开来的眼球运动异常情况。中心注视时的水平眼球震颤具有摆动和急跳波形，其幅度远低于其他形式先天性眼球震颤且视力为20/200 - 20/400的患者。在单眼视动刺激过程中，观察到慢相速度在数秒内缓慢增加以及视动性眼球震颤（OKN）的方向不对称性。OKN的方向不对称性表现为在视野中OKN鼓从颞侧到鼻侧旋转时的OKN增益（眼球速度/OKN鼓速度）高于鼓从鼻侧到颞侧旋转时的增益。在单眼视动刺激过程中，在无中心凹的动物（如兔子）中也发现了类似的方向不对称性和缓慢增加情况，但在正常人类受试者或其他形式先天性眼球震颤患者中未发现。
