Partsch G, Schwägerl W, Eberl R
Z Rheumatol. 1982 Jan-Feb;41(1):19-22.
Histamine, the decarboxylation product of histidine, was determined in serum, leucocytes, synovial fluid and synovial tissue rheumatic diseases. Histamine level was variable in most of the biological samples. In serum of patients with rheumatoid arthritis histamine was more frequent (50%) than in controls (10%). Leucocyte preparations containing basophile cells did not differ in their histamine concentration. Synovial fluid of rheumatoid arthritis patients showed histamine levels in the range of 1,0 to 23,4 ng/ml. The results were discussed by means of the pertinent literature.
组胺是组氨酸的脱羧产物,对风湿性疾病患者的血清、白细胞、滑液及滑膜组织中的组胺进行了测定。在大多数生物样本中,组胺水平存在差异。类风湿性关节炎患者血清中的组胺含量(50%)高于对照组(10%)。含嗜碱性细胞的白细胞制剂中的组胺浓度无差异。类风湿性关节炎患者滑液中的组胺水平在1.0至23.4纳克/毫升之间。并结合相关文献对结果进行了讨论。