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用于血红蛋白值异常的血液样本中铅检测的纸片打孔圆盘技术。

The paper punched disc technique for lead in blood samples with abnormal haemoglobin values.

作者信息

Carter G F

出版信息

Br J Ind Med. 1978 Aug;35(3):235-40. doi: 10.1136/oem.35.3.235.

DOI:10.1136/oem.35.3.235
PMID:698139
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1008412/
Abstract

A series of 15 blood samples with haemoglobin levels ranging from 4-6--16-1 g/dl were spotted on to Whatman No. 4 filter paper. Blood samples with low haemoglobin concentrations spread over a greater area of the filter paper than did those with high haemoglobin concentrations. This was further investigated by studying the performance of laboratory-prepared samples, and any effect on the estimation of blood lead value. Blood lead values assayed by the punched disc method on blood samples with low haemoglobin values were unreliable unless the estimated value was adjusted with respect to the area over which the blood had spread.

摘要

将一系列15份血红蛋白水平在4 - 6至16 - 1克/分升之间的血样点在沃特曼4号滤纸上。血红蛋白浓度低的血样在滤纸上的扩散面积比血红蛋白浓度高的血样更大。通过研究实验室制备样本的性能以及对血铅值估计的任何影响，对此进行了进一步研究。用打孔圆盘法测定血红蛋白值低的血样的血铅值是不可靠的，除非根据血液扩散的面积对估计值进行调整。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b964/1008412/c2e73a523ce4/brjindmed00075-0045-d.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b964/1008412/8dff3c7976d0/brjindmed00075-0045-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b964/1008412/64d7b146ead8/brjindmed00075-0045-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b964/1008412/44ab27318f67/brjindmed00075-0045-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b964/1008412/c2e73a523ce4/brjindmed00075-0045-d.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b964/1008412/8dff3c7976d0/brjindmed00075-0045-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b964/1008412/64d7b146ead8/brjindmed00075-0045-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b964/1008412/44ab27318f67/brjindmed00075-0045-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b964/1008412/c2e73a523ce4/brjindmed00075-0045-d.jpg

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本文引用的文献

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A micro-sampling method for the rapid determination of lead in blood by atomic-absorption spectrophotometry.一种通过原子吸收分光光度法快速测定血液中铅含量的微量采样方法。
Analyst. 1970 May;95(130):431-8. doi: 10.1039/an9709500431.
2
Determination of lead in capillary blood using a paper punched disc atomic absorption technique. Application to the supervision of lead workers.使用打孔圆盘原子吸收技术测定毛细血管血中的铅。应用于铅作业工人的监测。
Br J Ind Med. 1971 Oct;28(4):392-8. doi: 10.1136/oem.28.4.392.
3
Accuracy and precision of two methods of blood lead estimation.
两种血铅估算方法的准确性和精密度。
Br J Ind Med. 1973 Oct;30(4):394-5. doi: 10.1136/oem.30.4.394.
4
Determination of blood lead using a 4-0 mm paper punched disc carbon sampling cup technique.使用4-0毫米纸冲孔圆盘碳采样杯技术测定血铅。
Br J Ind Med. 1974 Jul;31(3):239-44. doi: 10.1136/oem.31.3.239.