Kocsis J D, Ruiz J A, Cummins K L
Exp Brain Res. 1982;47(1):151-3. doi: 10.1007/BF00235898.
Intra-axonal recordings were obtained in vitro from frog sciatic nerve axons. Adjusting whole nerve stimulation current to just subthreshold for the impaled axon elicited triphasic threshold changes in that axon. Threshold changes were determined by direct intra-axonal current application. Graded subthreshold depolarizations were present in many axons during the passage of action potentials in surrounding axons. When nerve branches were stimulated and axon recordings were obtained from the main nerve trunk, both branches, the one that activated the impaled axon and the one that did not, elicited threshold changes in the impaled axon. These data indicate on a cellular level that impulse activity in an intact nerve bundle can modulate the excitability of adjacent nonactivated fibers.
在体外从青蛙坐骨神经轴突获取轴突内记录。将整个神经刺激电流调整到刚好低于被刺入轴突的阈值，会在该轴突中引发三相阈值变化。阈值变化通过直接施加轴突内电流来确定。在周围轴突中动作电位传导期间，许多轴突中存在分级亚阈值去极化。当刺激神经分支并从主神经干获取轴突记录时，两个分支，即激活被刺入轴突的分支和未激活的分支，都会在被刺入轴突中引发阈值变化。这些数据在细胞水平上表明，完整神经束中的冲动活动可以调节相邻未激活纤维的兴奋性。
