Greenland S, Staisch K J, Brown N, Gross S J
Neurobehav Toxicol Teratol. 1982 Jul-Aug;4(4):447-50.
We conducted a prospective study of the effects of marijuana use in 35 pregnancies. Thirty-six age- and parity-matched nonuser pregnancies were selected for comparison. (Users of other illicit drugs were excluded from study.) Users and nonusers were similar with respect to most potentially confounding prenatal risk factors, although users tended to come from lower income and educational background. Most adverse outcomes of pregnancy were too infrequent to allow reliable comparisons between the groups, but the infants born to users exhibited significantly more meconium staining (57%, versus 25% in nonusers). Significant differences in duration of labor were also observed. Possible reasons for these findings are discussed.
我们对35例孕期使用大麻的影响进行了一项前瞻性研究。选取了36例年龄和胎次匹配的未使用大麻的孕妇作为对照。（其他非法药物使用者被排除在研究之外。）尽管使用者往往来自低收入和低教育背景，但在大多数可能造成混淆的产前风险因素方面，使用者和非使用者相似。大多数妊娠不良结局发生频率过低，无法在两组之间进行可靠比较，但使用者所生婴儿的胎粪污染明显更多（57%，而非使用者为25%）。在产程持续时间上也观察到了显著差异。本文讨论了这些发现的可能原因。
