Cheĭdo M A, Idova G V, Devoĭno L V
Biull Eksp Biol Med. 1982 Aug;94(8):82-4.
Haloperidol blockade of the dopaminergic system entails redistribution of functionally different cells. Suppressors of IgM and IgG response migrate, respectively, from the spleen and lymph nodes to the bone marrow whose cell transfer leads to inhibition of immune response. The data obtained indicate common regularities in cell distribution under blockade of the dopaminergic and activation of serotoninergic systems. Therefore, at the basis of inhibition of immunogenesis there lie monotypic processes of suppressor cell migration whatever the system responsible for it.
氟哌啶醇对多巴胺能系统的阻断导致功能不同的细胞重新分布。IgM和IgG反应的抑制细胞分别从脾脏和淋巴结迁移至骨髓，其细胞转移导致免疫反应受到抑制。所获得的数据表明，在多巴胺能系统阻断和5-羟色胺能系统激活的情况下，细胞分布存在共同规律。因此，无论负责免疫抑制的是何种系统，免疫发生抑制的基础都是抑制细胞迁移的单一型过程。
