Solanki D L, McCurdy P R, MacDermott R P
Am J Hematol. 1982 Sep;13(2):159-62. doi: 10.1002/ajh.2830130208.
A black woman with chronic lymphocytic leukemia (CLL) was found to have monoclonal B lymphocytes with one type of surface immunoglobulin and one variant of G6PD (glucose-6-phosphate dehydrogenase) (G6PD A). Erythrocytes and T cells contained both G6PD A and G6PD B and hence were of polyclonal origin. The CLL cells in this patient likely arose from a developmental stage later than the step of differentiation into T and B lymphocytes. Furthermore, her erythrocytes did not arise from a stem cell affected by the CLL process.
一名患有慢性淋巴细胞白血病（CLL）的黑人女性被发现其单克隆B淋巴细胞具有一种表面免疫球蛋白和一种葡萄糖-6-磷酸脱氢酶（G6PD）变体（G6PD A）。红细胞和T细胞同时含有G6PD A和G6PD B，因此它们起源于多克隆。该患者的CLL细胞可能起源于比分化为T和B淋巴细胞的步骤更晚的发育阶段。此外，她的红细胞并非起源于受CLL过程影响的干细胞。
