Rutsaĭ P V
Biull Eksp Biol Med. 1978 Sep;86(9):270-1.
On 8 cats chronic experiments were carried out to determine (spectrofluorometrically) the content of serotonin, dopamine, and noradrenaline in the sigmoid region of the left cerebral hemisphere on the second, third, forth, fifth, eighth days after the removal of the cortex of the symmetrical region of the right hemisphere. On the second day, at the time of maximum disorders of the locomotor function, dopamine content was found to decrease; there was also a tendency to reduction of noradrenaline and serotonin. On the third, and the fifth--eighth days, at the period of the locomotor activity restoration, there was a rise of serotonin content, whereas dopamine content remained low, and noradrenaline content rose considerably. The role of biochemical changes in the motor region in the mechanisms of locomotor function restoration following symmetrical damage of the large hemisphere cortex is discussed.
在8只猫身上进行了慢性实验，以（用荧光分光光度法）测定在切除右半球对称区域的皮质后的第二、三、四、五、八天，左大脑半球乙状结肠区域中血清素、多巴胺和去甲肾上腺素的含量。在第二天，在运动功能出现最大紊乱时，发现多巴胺含量下降；去甲肾上腺素和血清素也有下降趋势。在第三、五至八天，在运动活动恢复期间，血清素含量上升，而多巴胺含量仍然很低，去甲肾上腺素含量大幅上升。讨论了大半球皮质对称损伤后运动区域生化变化在运动功能恢复机制中的作用。
