Gordon T, Fisher M, Ernst N, Rifkind B M
Arteriosclerosis. 1982 Nov-Dec;2(6):502-12. doi: 10.1161/01.atv.2.6.502.
The association of diet with low density lipoprotein cholesterol (LDL-C) and total triglycerides, as well as with total and very low density lipoprotein cholesterol (VLDL-C), was investigated in a random sample of 4374 white participants aged 20 to 59 years seen by the Lipid Research Clinic Prevalence Study. Carbohydrate and total calories were negatively associated with LDL-C. There was also a statistically significant positive association of LDL-C with the percentage of total calories from fat. These three findings are generally consistent with what other cross-sectional studies have reported for the relation of diet with total cholesterol levels. The only diet variables significantly related to triglyceride levels in both men and women were the percentage of calories from fats, particularly polyunsaturated fatty acids (PFA), the P/S ratio, and the number of grams of PFA per day, all of which were inversely associated with the level of this lipid.
在脂质研究诊所患病率研究中，对4374名年龄在20至59岁的白人参与者的随机样本进行了调查，以研究饮食与低密度脂蛋白胆固醇（LDL-C）、总甘油三酯以及总胆固醇和极低密度脂蛋白胆固醇（VLDL-C）之间的关系。碳水化合物和总热量与LDL-C呈负相关。LDL-C与来自脂肪的总热量百分比之间也存在统计学上显著的正相关。这三项发现总体上与其他横断面研究报告的饮食与总胆固醇水平的关系一致。在男性和女性中，与甘油三酯水平显著相关的唯一饮食变量是来自脂肪的热量百分比，特别是多不饱和脂肪酸（PFA）、P/S比值以及每天的PFA克数，所有这些都与这种脂质的水平呈负相关。
