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核心技术专利：CN118964589B侵权必究

核心技术专利：CN118964589B侵权必究

Klemann S W, Pfohl R J

Comp Biochem Physiol B. 1982;73(4):907-14. doi: 10.1016/0305-0491(82)90335-2.

Creatine phosphokinase (CPK) isozymes found in Rana pipiens are similar to those found elsewhere; muscle-specific (MM-CPK), brain-specific (BB-CPK) and intermediate hybrid (MB-CPK) isozymes were identified. 2. Adult tissues exhibit CPK isozyme patterns similar to other vertebrates although variations are notable in nervous tissue, liver and kidney. 3. CPK isozyme patterns in ovarian eggs, ovulated eggs and selected stages of early development demonstrate a significant rise in CPK with neurulation. Most notable is a sharp increase in brain-specific BB-CPK. 4. MM-CPK purified from skeletal muscle is found to be similar, in properties studied, to the corresponding isozyme in other vertebrate species.

在牛蛙中发现的肌酸磷酸激酶（CPK）同工酶与在其他地方发现的相似；鉴定出了肌肉特异性（MM-CPK）、脑特异性（BB-CPK）和中间杂种（MB-CPK）同工酶。2. 成年组织的CPK同工酶模式与其他脊椎动物相似，尽管神经组织、肝脏和肾脏存在明显差异。3. 卵巢卵、排卵卵和早期发育选定阶段的CPK同工酶模式显示，随着神经胚形成，CPK显著增加。最显著的是脑特异性BB-CPK急剧增加。4. 从骨骼肌中纯化的MM-CPK在研究的特性方面与其他脊椎动物物种的相应同工酶相似。

Klemann S W, Pfohl R J

Comp Biochem Physiol B. 1982;73(4):907-14. doi: 10.1016/0305-0491(82)90335-2.

Creatine phosphokinase (CPK) isozymes found in Rana pipiens are similar to those found elsewhere; muscle-specific (MM-CPK), brain-specific (BB-CPK) and intermediate hybrid (MB-CPK) isozymes were identified. 2. Adult tissues exhibit CPK isozyme patterns similar to other vertebrates although variations are notable in nervous tissue, liver and kidney. 3. CPK isozyme patterns in ovarian eggs, ovulated eggs and selected stages of early development demonstrate a significant rise in CPK with neurulation. Most notable is a sharp increase in brain-specific BB-CPK. 4. MM-CPK purified from skeletal muscle is found to be similar, in properties studied, to the corresponding isozyme in other vertebrate species.

在牛蛙中发现的肌酸磷酸激酶（CPK）同工酶与在其他地方发现的相似；鉴定出了肌肉特异性（MM-CPK）、脑特异性（BB-CPK）和中间杂种（MB-CPK）同工酶。2. 成年组织的CPK同工酶模式与其他脊椎动物相似，尽管神经组织、肝脏和肾脏存在明显差异。3. 卵巢卵、排卵卵和早期发育选定阶段的CPK同工酶模式显示，随着神经胚形成，CPK显著增加。最显著的是脑特异性BB-CPK急剧增加。4. 从骨骼肌中纯化的MM-CPK在研究的特性方面与其他脊椎动物物种的相应同工酶相似。