Lateral mobility in reconstituted membranes--comparisons with diffusion in polymers.

The diffusion coefficients (D) of lipopolysaccharide, phospholipid, and Escherichia coli matrix protein were determined in reconstituted multibilayer membranes. Over a range of protein concentration of 0--60% by weight, D for lipopolysaccharide decreased 10-fold, whereas D for phospholipid remained essentially constant. The diffusion coefficient of matrix protein at a concentration of 50% was less than or equal to 10(-12) cm2 s-1. These results are discussed in terms of a model for diffusion in polymeric networks.