酒精戒断：癫痫发作大鼠中插管乙醇的延迟分布
Alcohol withdrawal: delayed distribution of intubated ethanol in rats having seizures.
作者信息
Lindros K O
出版信息
Drug Alcohol Depend. 1980 Mar;5(3):167-70. doi: 10.1016/0376-8716(80)90175-1.
PMID:6986246
Abstract
Tail blood ethanol levels two hours after acute oral administration of ethanol to rats during withdrawal from chronic ethanol feeding were much lower in rats with previous seizures than in non-convulsing rats. Since ethanol elimination rates were similar, this suggests that in the convulsive state the distribution of ethanol to the periphery is severely inhibited.
摘要
在从慢性乙醇喂养中撤药期间，对大鼠急性口服乙醇后两小时，既往有癫痫发作的大鼠尾血乙醇水平比无惊厥的大鼠低得多。由于乙醇消除率相似，这表明在惊厥状态下，乙醇向周围组织的分布受到严重抑制。
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