Lougheed W, Albisser A M
Int J Artif Organs. 1980 Jan;3(1):50-6.
Insulin delivery mechanisms in which the polypeptide is conducted through the fine bore tubes develope luminal occlusions after 2-6 weeks. Scanning electron micrographs of the ends of such capillaries reveal that the usual methods of sectioning these tubes produces barbed and distorted exits on which aggregates of insulin appear to be localized. This paper addresses a novel technique for sectioning teflon (PTFE) capillary bore tubing which avoids this problem.
胰岛素输送机制中，多肽通过细孔管传导，在2至6周后会出现管腔堵塞。此类毛细管末端的扫描电子显微镜图像显示，常规的这些管子切片方法会产生带刺且扭曲的出口，胰岛素聚集体似乎就定位在这些出口处。本文介绍了一种用于聚四氟乙烯（PTFE）毛细管细孔管切片的新技术，该技术可避免此问题。
