Prange C H, Bach D, Kessler M
Urol Int. 1980;35(1):20-3. doi: 10.1159/000280300.
Presensitization induced by pretreatment of the recipients with donor species-specific spleen antigen cannot be completely reversed by immunosuppressive drugs. However, there is a suppressive influence of the combined administration of azathioprine and prednisolone on hemagglutinating antibody production after transplantation as well as an effect on function and survival time of renal xenografts.
用供体物种特异性脾脏抗原对受体进行预处理所诱导的预致敏不能被免疫抑制药物完全逆转。然而,硫唑嘌呤和泼尼松龙联合给药对移植后血凝抗体产生有抑制作用,并且对肾异种移植物的功能和存活时间也有影响。